Excellent paper demonstrating how low heart rate variability (HRV) is associated with increased inflammation. High-frequency heart rate variability (HF-HRV) had the strongest inverse relationship with proinflammatory cytokines. HF-HRV represents the functionality of the vagus nerve, the conduit of all parasympathetic signaling.The vagus nerve can lose function because of chronically elevated blood sugar, chemotherapies, and ironically chronic inflammation from bacterial overgrowth or imbalances of omega-3 and omega-6 fatty acids. When the vagus nerve fails, the inflammation jumps even further since the Vagus nerve is the primary mechanism that controls inflammation. Fortunately, treatment through vagus nerve stimulation is a way to regain control
Nemechek Technologies is a fast-growing company with unique expertise in bioelectric neuromodulation.We are positioned to provide a variety of solutions for individuals suffering from the effects of COVID-19 infection, brain injury, developmental disorders, and medical conditions driven by chronic inflammation. We are currently looking for interested partners to fulfill our mission.
innovative bioelectric technology
As the Coronavirus pandemic continues to spread worldwide, it is becoming readily apparent that modern medicine is not prepared to fight the unique disease processes triggered by COVID-19 infection. Nemechek Technologies is a small company with cutting edge expertise and a clear vision of the medical needs of patients afflicted with COVID-19.
Our company’s vision for growth arose from Dr. Nemechek’s 20 years of experience as an HIV expert, combined with his recent discoveries involving the reversal of nervous system damage through the proper regulation of inflammation within the body. Dr. Nemechek believes that the future of health maintenance will be based on minimizing the stress of systemic inflammation.
Our Mission is to demonstrate that vagus nerve stimulation is an effective therapy for acute and convalescent COVID-19 illness as well as a wide variety of chronic inflammatory and neurological conditions. We are working to bring an FDA-approved vagus nerve stimulator to the marketplace.
How Bioelectric Neuromodulation Can Aid in the Fight Against COVID-19
Patients hospitalized with COVID-19 are predominantly dying of respiratory failure due to a surge of pro-inflammatory protein molecules called cytokines that regulate inflammation. In some COVID-19 patients, an excessive inflammatory reaction known as a “cytokine storm” will trigger acute respiratory distress syndrome. This severe form of lung injury is why many patients require mechanical ventilation.
A potential solution to this deadly, unregulated immune response may be a mild electrical current applied to the vagus nerve. Dr. Nemechek’s method, known as transcutaneous auricular vagus nerve stimulation (taVNS), delivers a barely perceptible micro-current through a specially designed clip that fits comfortably on the ear.
Nemechek Technologies has sponsored a clinical trial that demonstrated the use of VNS in hospitalized COVID-19 patients was associated with low mortality and the infrequent use of mechanical ventilation. In addition, Dr. Nemechek was recently awarded a U.S. PATENT for methods of treating COVID-19 Induced Cytokine Storm.
With these advances in hand, Nemechek Technologies, LLC is seeking an Emergency Use Authorization (EUA) from the FDA to use taVNS as adjunctive therapy in persons struggling with the acute or chronic symptoms of COVID-19 infection.
Research:Transcutaneous auricular vagus nerve stimulation influences gastric motility: A randomized, double-blind trial in healthy individuals
Another excellent example of the growing clinical utility of transcutaneous vagus nerve stimulation. https://pubmed.ncbi.nlm.nih.gov/34187756/
Vagus nerve stimulation (VNS) has a wide range of potentially powerful effects. Another study has demonstrated increased stroke recovery when VNS is combined with physical therapy. The study involved 19 rehabilitation centers within the U.S. and U.K. and involved 108 participants. The patients whose strokes had occurred an average of 3 years prior whose received rehabilitation 3 times a week for 6 weeks followed by a home exercise program. VNS was used in conjunction with therapeutic exercise. About twice as many participants in the VNS group achieved clinically meaningful improvement in arm function. Ninety days after in-clinic therapy, 47%of this
Using transcutaneous vagus nerve stimulation (tVNS) for 2 minutes, 3 times per day reduces inflammation markers in the bloodstream and improves symptoms from psoriatic arthritis and ankylosing spondylitis. In addition to other studies showing benefits in rheumatoid arthritis and Crohn’s disease, this study provides additional evidence that tVNS may be an effective anti-inflammatory therapy for a variety of autoimmune disorders.
Research: Vagus nerve stimulation as a potential adjuvant to behavioral therapy for autism and other neurodevelopmental disorders
The authors of this paper discuss how VNS paired with behavioral therapy may represent a potential new approach to enhance rehabilitation that could significantly improve the outcomes of individuals with neurodevelopmental disorders. ‘